Born on February 22, 1945, in Kansas City, Missouri, Charleson embarked on her acting career in the 1960s, with early roles in soap operas such as A Flame in the Wind and As the World Turns. In 1977, she joined the cast of General Hospital, stepping into the role of Dr. Monica Quartermaine. Over nearly five decades, she became a central figure on the show, appearing in over 2,000 episodes and earning four Daytime Emmy Award nominations for Outstanding Lead Actress in a Drama Series.
Throughout her tenure, Charleson's character was integral to many of the show's most memorable storylines, including a notable love triangle and a poignant battle with breast cancer. Her dedication to the role and her compelling performances resonated deeply with audiences, solidifying her status as a beloved figure in daytime television.
In addition to her work on General Hospital, Charleson made guest appearances on various television series, including Happy Days and Friends. She also had roles in films such as The Day of the Dolphin and the television thriller Revenge!.
Charleson's health had declined in recent years, leading to her final appearance on General Hospital in December 2023. Despite her absence, her character continued to be referenced on the show, reflecting her enduring impact on the series.
Her passing marks the end of an era for General Hospital and its devoted viewers. As Valentini expressed, "I will miss our daily chats, her quick wit, and incredible presence on set." Leslie Charleson leaves behind a legacy of talent, dedication, and a lasting impression on the world of daytime television.
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